MULCh: ModULes for the analysis of Contrast variation data

The purpose of this set of programs is to allow the extraction of structural parameters from Neutron Contrast Variation data for two component systems. There are three modules to facilitate this:

Contrast: This module determines the contrast ("scattering power" relative to the solvent) for each subunit in the complex for various proportions of D2O in the solvent. The contrast is important for the subsequent modules
Rg: Analyses the dependence of the radius of gyration upon contrast. From this analysis information can be extracted relating to the radii of gyration of each subunit and their separation.
Compost: Decomposes the scattering profiles down to scattering from each subunit, and a cross term, related to the disposition of each.

Testing and basic description of the work has been published: A.E. Whitten, S. Cai and J. Trewhella, J. Appl. Crystallogr. If this page is used we ask that you cite that article.

The MULCh manual can be found here

The source code for the modules can be found here

Test data and input files for MULCh can be found here